Cerberus should be the leader. What you want from him is the healing ability in 1 turn and Larva's 1 turn def buff.
Now, keep in mind that what you need to have plenty of runes to be as close to 4k def as you can. Keep in mind, though, that in Legend, fully runed teams, even with Larva's buff, can deal 630ish damage, so you have to consider HP and the ability to kill at least a mon at your 2nd turn.
This is why 1 turn medium damagers are also valuable. Try considering all your available options, taking into account runes.
I guess with those mons plus some modest runes you